Tryptophan-dehydrobutyrine diketopiperazine, a metabolite of Streptomyces spectabilis.
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منابع مشابه
Kanchanamycins, new polyol macrolide antibiotics produced by Streptomyces olivaceus Tü 4018. I. Taxonomy, fermentation, isolation and biological activities.
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Local catabolism of the amino acid tryptophan (Trp) by indoleamine 2,3-dioxygenase (IDO) is considered an important mechanism of regulating T cell immunity. We show that IDO transcription was increased when myelin-specific T cells were stimulated with tolerogenic altered self-peptides. Catabolites of Trp suppressed proliferation of myelin-specific T cells and inhibited production of proinflamma...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1974
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.27.733